Lou Anne Guilford, 53, of Lafayette, passed peacefully on Oct. 5, 2016, following her battle with ovarian cancer. She was born in Hawkinsville, Ga., on July 13, 1963, to the late Larry and Ruth Jo Pyle. Following her mother’s death in 1964, she was raised by her paternal grandparents, Ernest and Zula Pyle, and her father until he remarried in 1967. She was adopted by her stepmother Sue Borton Pyle who survives. She was a graduate of Tippecanoe Valley High School in 1981 and Purdue University in Lafayette in 1985. She lived in Georgia, Tennessee, Florida, and Indiana throughout her life, but always considered the family farm in Mentone to be her home. While living in Florida, she met the love of her life, her husband, David Guilford. Together, they spent many years happily married and raised two sons, Corey and Cody. She enjoyed running, biking, swimming, camping, drawing, painting, and writing. She was a loving and devoted mother, wife, and true and trusted friend to many. She was a dedicated and valued employee, working in Analytical Chemistry, Information Technology, and Instructional Design for the same company for 28 years. She is survived by her husband and best friend David Guilford; her sons Corey and Cody Guilford of Lafayette; a stepmother, Sue Pyle; two brothers, (Kevin and spouse Janet) Pyle, and Brian (and spouse Melissa) Pyle; many nieces and nephews, extended family and friends. She was preceded in death by a sister, Jennifer Pyle Witham; her grandparents and many extended family members. Services will be 3 p.m., Tuesday at Bethany Presbyterian Church, 3305 Longlois Drive, Lafayette, with visitation one hour prior to services. Another memorial service will be held at 3 p.m., Thursday at King Memorial Home, 101 N. Tucker St., Mentone with visitation one hour prior to the service. The Rev. Kevin Bowers will officiate. Burial will be at Mentone Cemetery in Mentone. ***** Memorials to Camp Mak-A-Dream, P.O. Box 1450, Missoula, Montana, 59806, or the National Alliance of Ovarian Cancer Survivors to the Ovarian Cancer Research Fund Alliance, P.O. Box 32141, New York, NY 10087-2141 Condolences via www.hartzlerfuneralservices.com.